Microfluidic Platforms for Lab Automation
This microfluidic technique enables inexpensive, portable and automated bioinstruments. In order to develop a autonomous, miniaturized bio-analysis platform, a microfluidic sample processor with sufficient programmability for a wide range of sample processing operations is essential. Using both pneumatic actuations, digital microfluidicsand paper-based microfluidics, we are developing an automated, miniaturized and programmable microfluidic platform.
Biomedical Devices for Personalized Medicine
Personalized medicine uses information from a patient's genetic/proteomic profile to determine appropriate dosage. By genetic and proteomic analysis, doctor can prescribe exact amount medicine to patients. Current measurement devices are complicated process and need intensive sample preparation steps. Our lab actively seek new type of biomedical tools to know the drug response from a single drop of samples precisely and rapidly.
Both disease mechanism studies and drug tests generally require whole animals or freshly dissected body parts. Such experiments are costly, and can raise ethical issues. In vitro microphysiological biosystems could reduce these issues and provide alternative models. The systems are particularly well-suited for multi-variable bioassays, offering systematic control of all experimental variables. In addition, the biomimetic system can be replicated to create a high-throughput experimental platform for hundreds of experiments simultaneously. With these advantages, the biomimetic system reduces discovery time and the consumption of expensive reagents and cells, and allows the integration of detection assays directly in the microsystems.
Other Research Topics
- Smart flexible electronics for biosignal monitoring
- Smart microneedle to monitor drug efficacy
- Smart surface tuning surface topology
- Pneumatically actuated softrobot