Molecular Pathology (AHMP)

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5000 Level Courses

5100. Issues in Molecular Pathology I (1:1:0). Presentation of current topics regarding the biomedical application of genetic information using a journal club format. Ethical issues and principles of educational methodologies will also be discussed.

5300. Applied Statistics and Research (3:2:3). Introduction to descriptive, inferential, and non-parametric statistics related to basic and clinical science; introduction to the process of basic and clinical research and research design.

5301. Management of the Molecular Laboratory (3:3:1). Business and management principles relative to laboratory management and administration will be presented. The purpose, function, and utilization of laboratory services in coordination with specimen procurement, patient education and consent, regulatory issues, and quality assurance are discussed. Specific requirements regarding certification of molecular pathology clinical laboratories will be reviewed and discussed.

5309. Human Molecular Genetics (3:3:0). This course covers DNA structure and function, chromosomes, cells and development, pedigree analysis, and reviews the basic techniques used in the laboratory. In addition, various genome sequencing projects and the insights they provide into the organization, expression, variation, and evolution of our genome, especially as they relate to the study and treatment of human disease are discussed. Discussion of mapping, identifying, and diagnosing the genetic causes of mendelian and complex diseases and cancer. (Writing Intensive)

5405. Applied Molecular Techniques I (4:3:6). Introduction to basic genetic testing techniques used in molecular and forensic pathology with discussion of quality laboratory practice including quality control, quality assurance, and quality improvement. Lab component will focus on the use of DNA and RNA technologies in clinical settings in addition to their use in identity testing. (Writing Intensive)

5406. Molecular Biology of the Cell (4:4:0). Comprehensive survey course in eukaryotic molecular biology and genetics required by all students planning a career in molecular pathology or basic biomedical research.

5407. Pathophysiology (4:4:0). Presentation of the basis of human disease with regard to the major determinants of disease in human organ systems with discussion of normal anatomy and physiology. Survey of the clinical laboratory that includes common laboratory assays in Hematology, Clinical Chemistry, and Microbiology and addresses the purpose, function, and utilization of laboratory services. Specimen procurement, patient education and consent, and quality assurance are discussed.

5408. Applied Molecular Techniques II (4:3:6). Prerequisite: AHMP 5405. Advanced training and technical experience in the use of DNA and RNA technologies applied to the clinical setting. Independent work on research project. (Writing Intensive)

5741. Graduate Research (V1-3). Supervised independent advanced molecular clinical research in an affiliated laboratory. Course culminates in the preparation of an original scientific paper and public presentation of the research project. (Writing Intensive)

5742. Clinical Preceptorship (V1-3). Supervised advanced molecular clinical practicum in an affiliated laboratory with emphasis on patient testing, quality assurance, and case studies assessment.

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