Dr. Yehia Mechref has been working for years on the development of mass spectrometric bioanalytical approaches that allows the detection of changes in carbohydrates and proteins at high sensitivity. These approaches have been recently adopted to monitor changes associated with glycans attached to blood proteins to detect cancer at early stages. According to Dr. Mechref, "The ability to detect the changes in these 'sweet' molecules is going to allow better understanding of cancer development and progression which will subsequently permit early detection of this disease." Dr. Mechref's group is currently working on defining sugar structures that will allow distinguishing different cancer type.
Dr. Mechref received his doctorate in analytical chemistry from Oklahoma State University with honorable mention after majoring in chemistry at the American University of Beirut, Lebanon. From September 1997 through December 2000, Dr. Mechref assumed a faculty position in the Department of Chemistry at the United Arab Emirates University (Al-Ain, United Arab Emirates).
Prior to joining TTU, Dr. Mechref was the director of METACyt Biochemical Analysis Center and the assistant director of the National Center for Glycomics and Glycoproteomics. Dr. Mechref is a member of the editorial boards of the Journal of Glycomics and Lipidomics and the Journal of Spectroscopy and Dynamics. Dr. Mechref has more than 97 publications in peer-referred journals, nine patents, seven review articles and nine book chapters. Dr. Mechref has organized many symposia and chaired several sessions at national and international conferences, and he is a co-author of more than 150 presentations at national and international meetings. Dr. Mechref has co-guest edited a special issue of Mass Spectrometry Reviews and guest edited a special issue of Current Proteomics. Currently, he is guest editing a special issue of Electrophoresis.