College of Arts & Sciences, Department of Biological Sciences
Dr. Karamysheva studies the roles of exosomes in the pathogenesis of Leishmania parasites. She also works on identification of sphingosine kinase important for survival and virulence of protozoan parasites. Dr. Karamysheva received her PhD in Molecular Biology from Moscow State University in Russia. She performed her postdoctoral studies on protein translation termination in the Department of Tumor Biology, University of Tokyo, Japan. Later on during her postdoctoral training at Texas A&M University she discovered that ciliated protozoan Euplotes crassus achieves a developmental switch in the telomerase catalytic subunit through programmed gene elimination (Cell, 2003). Before joining TTU Dr. Karamysheva was a Research Faculty at UT Southwestern Medical Center where she studied the role of amino acid transporter SLC6A14 in inflammation, infection and pathogenesis of cystic fibrosis disease. She also performed research on cell cycle and participated in the teamwork on the project that led to the discovery of a novel quality pathway where aberrant protein expression leads to the elimination of its own mRNA template.
Recent Scholarship: Karamysheva Z, Díaz-Martínez LA, Warrington R, Yu H. 2015. Graded requirement for the spliceosome in cell cycle progression. Cell Cycle. 14(12): 1873-1883.