From I-10 West:
Take the Texas Tech University exit to Loop 481. Turn left on FM 2169. TTU is located at the end of FM 2169.
From I-10 East:
Take the HWY 83 exit onto Main Street. At the traffic light, turn right on HWY 377. At the Texas Tech University sign, turn left on Flat Rock Lane. Turn right at the Yield sign onto campus.