Department of Pharmaceutical Sciences

Professor Quentin R. Smith, Chairperson.

Professors Khan, Mehvar, Reddy, and Shah; Associate Professors Bickel, Thekkumkara, Weis, and Wright; Assistant Professors Abbruscato, Allen, Bouma, Fisher, Lindsey, Roder, Stoll, and Weidanz.

This department offers study in the following graduate degree programs: PHARMACEUTICAL SCIENCES, Master of Science and Doctor of Philosophy in the Texas Tech School of Pharmacy at Amarillo. Pharmaceutical sciences encompass all those areas of pharmacy research that pertain to drug design, delivery, formulations, and therapeutics. The faculty members of the department exhibit research interests and expertise in drug design and delivery, pharmacology, pharmaceutics (including formulations and industrial pharmacy), pharmacokinetics, drug receptor modeling, molecular and reproductive biology, biochemistry, pathophysiology, immunology and cancer therapy, toxicology, and pharmacy administration. The graduate program in pharmaceutical sciences is designed to train students for careers in pharmaceutical industry, academia, and federal agencies including the FDA. Admissions requirements include a degree in pharmacy, chemistry, biology, or related areas and GRE scores of at least 1100 in the verbal and quantitative sections, and a TOEFL score of at least 550 (written) or 213 (electronic) for international students. Teaching and research assistantships are awarded on a competitive basis. The departmental courses are listed below. Additional required and elective courses have been arranged through the Departments of Chemistry and Biochemistry, Geology, and Mathematics and Statistics of Texas Tech University, and through the Departments of Physiology and Pharmacology of Texas Tech University Health Sciences Center. For more information contact Dr. Mansoor A. Khan, Director of Graduate Programs, (806) 356-4000 ext. 285.

Courses in Pharmaceutical Sciences. (GPSC)

5101. Topics in Pharmacology (1:1:0). Special topics in pharmaceutical sciences that are not normally included in other courses. May be repeated for credit with change in content.

5201. Topics in Pharmacology (2:2:0). Special topics in pharmaceutical sciences that are not normally included in other courses. May be repeated for credit with change in content.

5301. Topics in Pharmacology (3:3:0). Special topics in pharmaceutical sciences that are not normally included in other courses. May be repeated for credit with change in content.

5304. Principles of Drug Action (3:3:0). Principles that govern drug action within the body (pharmacodynamics) as well as drug absorption, distribution, metabolism, and excretion (pharmacokinetics).

5307. Pharmaceutical Sciences Research Methods (3:3:3). A lecture and laboratory course designed to provide an overview of current research methods in pharmaceutical sciences under direct guidance of a faculty member.

5310. Drug Design and Discovery (3:3:0). Prerequisite: GPSC 5304. Overview of the new methods for quantitative SAR, computer-aided drug design, mass screening, and combinatorial chemistry.

5320. Drug Metabolism (3:3:0). Analysis of the primary metabolic enzymatic systems that are involved in the clearance of drugs from the body and the mechanisms that regulate their activity.

5330. Pharmacokinetics (3:3:0). A quantitative treatment at the graduate level of the dynamics of drug disposition in the body and the national design of drug dosage regimens.

5340. Molecular Drug Action (3:3:0). Analysis of drug action at the molecular level, including molecular biology and signal transduction.

5350. Advanced Pharmaceutics (3:3:0). Prerequisite: DDS3 or equivalent. Quantitative treatment of reactions of pharmaceutical interest. Drug decomposition, approaches to stabilization and preservation, accelerated stability analysis, complexation and micromeritics.

5360. Industrial Pharmacy (3:3:0). Principles of formulation of powders, capsules, and compressed and coated tablets for conventional and controlled drug delivery.

5370. Biotechnology (3:3:0). An introduction to the area of molecular biology, genomics, and protein chemistry.

5380. Special Topics in Drug DesignImmunopharmacology (3:3:0). Principles of disease treatment with focus on the immunological system and new advances in immunotherapy.

5390. Pharmaceutical Science Research Design and Analysis (3:3:0). Overview of experimental design implementation and data analysis, including biostatistics for pharmaceutical science investigations.

5440. Biopharmaceutics (4:4:0). Prerequisite: DDS3 and kinetics or equivalent. Advanced treatment of the influence of dosage forms, route of administration, and dosage regimen on drug availability and newer technologies for targeting drug delivery to specific organs and cell types.

6000. Master's Thesis (V1-6).

7000. Pharmaceutical Sciences Research (V1-12).

7101. Pharmaceutical Sciences Seminar (1:1:0). Weekly seminar series designed to provide training in research data presentation and analysis.

8000. Doctor's Dissertation (V1-12).

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