The Cayuse IRB Review Process
Researchers can track the review process of their submissions by looking at the Dashboard at the top of the Submission Details screen.
The green check mark indicates the requirements are complete for that review stage. The highlighted gray section shows where the submission is in the review process.
Cayuse IRB Test Site Available for Practice/Familiarization
The Sandbox UAT provides users a chance to practice or familiarize themselves with Cayuse IRB using a test site. The site allows test studies to be created providing practice before submitting a study through Cayuse IRB. Studies created in the Sandbox UAT are never processed.
To access the practice site, click on "Sandbox UAT" above. Enter session23 (lower case) as the user name and ttuttu as the password.
Cayuse IRB help files and "How To" Power Point presentations are also available to help guide you through the submission process.
Cayuse IRB Training Tutorials and PowerPoints
- Cayuse IRB: Basics
- Cayuse IRB: Creating a New Submission
- Adding Co-Investigators to Legacy Studies
- Modifications to Legacy Studies
- Cayuse IRB Help Tutorials
Request Training for your Group
Colleges, departments and organizations may request a Cayuse IRB training session for faculty, staff, and/or students. Please contact the HRPP office to schedule training at 806-742-2064 or email us at HRPP@ttu.edu.
Tip of the Month
Study vs Submission
Cayuse IRB can be somewhat confusing for first time users, especially when it comes to the new terminology and processes. What we used to call protocols are now studies; the old paper IRB proposals are submissions; amendments are now modifications...Technology alone changed the manner in which we refer to our processes.
So to put things in a practical perspective (paper & file cabinet), when you create a study in Cayuse IRB, you are in effect creating a file folder and a 5x7 index card with the basic information. All of that appears on the Study Details screen including a system generated IRB number. When you click on Add Submission, you are creating another 5x7 card and beginning the IRB application process by way of an "Initial Submission". It's the initial submission that has to be approved by the IRB in order to conduct human subject research.
Now, fast forward to the future when you want to make changes to the approved initial submission. You are able to open your study from the Cayuse IRB Dashboard. In the top right corner of the Study Details screen, the New Submission button should be active. From here, you can create another submission within the confines of the study (folder). They include modifications, incidents, withdrawals, and closures. All of the different submissions you create are located in the study folder (Study Details).
Once you understand the terminology, the rest is simply knowing where and what to click on. Good luck!
What does it mean to be a Research Principal Investigator at Texas Tech University?
The Office of Human Research Protections (HHS/OHRP, 2016)) describes the role and
responsibilities of a research investigator in the following way:
"Investigators play a crucial role in protecting the rights and welfare of human subjects and are responsible for carrying out sound ethical research consistent with research plans approved by an IRB. Along with meeting the specific requirements of a particular research study, investigators are responsible for ongoing requirements in the conduct of approved research that include, in summary:
- obtaining and documenting informed consent of subjects or subjects' legally authorized representatives prior to the subjects' participation in the research, unless these requirements have been waived by the IRB (45 CFR 46.116; 45 CFR 46.117);
- obtaining prior approval from the IRB for any modifications of the previously approved research, including modifications to the informed consent process and document, except those necessary to eliminate apparent immediate hazards to subjects (45 CFR 46.103(b)(4)) ; and
- ensuring that progress reports and requests for continuing review and approval are
submitted to the IRB in accordance with the policies, procedures, and actions of the
IRB as referenced in the institution's OHRP-approved Federalwide assurance (45 CFR
46.103(b)(4), 45 CFR 46.109(e), 45 CFR 46.115(a)(1)) . In certain circumstances, investigators
also would be responsible for meeting the following additional regulatory requirements:
- providing to the IRB prompt reports of any unanticipated problems involving risks to subjects or others 45 CFR 46.103(b)(5);
- providing to the IRB prompt reports of serious or continuing noncompliance with the regulations or the requirements or determinations of the IRB (45 CFR 46.103(b)(5)); and
- keeping certain records as required by the HHS regulations for at least three years after completion of the study."
TTU Policy 74.09 (5) outlines the criteria for those researchers who are eligible
to assume the responsibilities as a Principal Investigator (PI) over a research study.
The Principal Investigator must be:
• a full time faculty member; or
• a tenured faculty member; or
• a full time employee with a terminal degree in his/her discipline.
Human Research Protection Program
Administration Building, Room 357
Box 41075 | MS 1075
Lubbock, TX 79409-1075
(806) 742-2064 Office| (806) 742-3947 Fax
April IRB Meeting - April 25 @ 3 p.m.
Next Meeting - May 30 @ 3 p.m.
Full Board proposals due May 9th
March HRPP/IRB Stats:
- 174 Reviews Assigned
- 80 Were Initial Submissions
- 106 Proposals Approved
- 45 Undergoing IRB Review
Leaving for Summer Break?
From the Dashboard under 'Studies Expiring' Cayuse IRB users can set the view to see those studies due to expire anywhere from 30, 60 or 90 days out.