Texas Tech University
Human Research Protection Program (HRPP)


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Cayuse IRB

The Cayuse IRB Review Process
Researchers can track the review process of their submissions by looking at the Dashboard at the top of the Submission Details screen.

Cayuse IRB Review Process

The green Check check mark indicates the requirements are complete for that review stage. The highlighted gray section shows where the submission is in the review process.

Cayuse IRB Test Site Available for Practice/Familiarization
The Sandbox UAT provides users a chance to practice or familiarize themselves with Cayuse IRB using a test site. The site allows test studies to be created providing practice before submitting a study through Cayuse IRB. Studies created in the Sandbox UAT are never processed.

To access the practice site, click on "Sandbox UAT" above. Enter session23 (lower case) as the user name and ttuttu as the password.

Cayuse IRB help files and "How To" Power Point presentations are also available to help guide you through the submission process.

Cayuse IRB Training Tutorials and PowerPoints


Request Training for your Group
Colleges, departments and organizations may request a Cayuse IRB training session for faculty, staff, and/or students. Please contact the HRPP office to schedule training at 806-742-2064 or email us at HRPP@ttu.edu.

Hot Topics

What does it mean to be a Research Principal Investigator at Texas Tech University?

The Office of Human Research Protections (HHS/OHRP, 2016)) describes the role and responsibilities of a research investigator in the following way:
"Investigators play a crucial role in protecting the rights and welfare of human subjects and are responsible for carrying out sound ethical research consistent with research plans approved by an IRB. Along with meeting the specific requirements of a particular research study, investigators are responsible for ongoing requirements in the conduct of approved research that include, in summary:

  • obtaining and documenting informed consent of subjects or subjects' legally authorized representatives prior to the subjects' participation in the research, unless these requirements have been waived by the IRB (45 CFR 46.116; 45 CFR 46.117);
  • obtaining prior approval from the IRB for any modifications of the previously approved research, including modifications to the informed consent process and document, except those necessary to eliminate apparent immediate hazards to subjects (45 CFR 46.103(b)(4)) ; and
  • ensuring that progress reports and requests for continuing review and approval are submitted to the IRB in accordance with the policies, procedures, and actions of the IRB as referenced in the institution's OHRP-approved Federalwide assurance (45 CFR 46.103(b)(4), 45 CFR 46.109(e), 45 CFR 46.115(a)(1)) . In certain circumstances, investigators also would be responsible for meeting the following additional regulatory requirements:
    • providing to the IRB prompt reports of any unanticipated problems involving risks to subjects or others 45 CFR 46.103(b)(5);
    • providing to the IRB prompt reports of serious or continuing noncompliance with the regulations or the requirements or determinations of the IRB (45 CFR 46.103(b)(5)); and
    • keeping certain records as required by the HHS regulations for at least three years after completion of the study (45 CFR 46.115(b))."

TTU Policy 74.09 (5) outlines the criteria for those researchers who are eligible to assume the responsibilities as a Principal Investigator (PI) over a research study. The Principal Investigator must be:
• a full time faculty member; or
• a tenured faculty member; or
• a full time employee with a terminal degree in his/her discipline.

More Hot Topics >>

HRPP/IRB Announcements

We can help! Having difficulty understanding the Cayuse IRB submission process or you have questions? The HRPP staff is available to help you and/or your colleagues by way of a phone call, individual consultations or presentations to your group. Call us at 742-2064.

IRB Meeting
Oct. 25, 2016 @ 3 p.m.
Full Board submissions due by Oct. 4

Next IRB Meeting
Nov. 29, 2016 @ 3 p.m. (Tentative)
Full Board submissions due by Nov. 8

View Calendar for More Events >>

Sept. 2016 HRPP Statistics

127 Reviews Assigned
58 Initial Submissions
126 Proposals Approved

Tip of the Month
Confused about how to create a Renewal, Modification, Incident or Closure for an existing Cayuse IRB study? It's only a click away. Here's the short version. Open the study from the Dashboard. At the top right corner, click on New Submission. A drop down table containing the options will display. Select the type of submission you would like to create. For a more detailed version with step by step directions, go to the Training tab on the HRPP website and check out the 'How to PowerPoint instruction guides.

More Useful Tips >>

Cayuse IRB
In January 2016, Microsoft ended support for Internet Explorer 9 & 10. In light of this, Evisions will discontinue IE9 & 10 compatibility support for all products in the Research Suite (Cayuse 424, SP, & IRB) on July 1, 2016.

Human Research Protection Program
Administration Building, Room 357
Box 41075 | MS 1075
Lubbock, TX 79409-1075
(806) 742-2064 Office| (806) 742-3947 Fax


Office of the Vice President for Research