Jannette Dufour, Ph.D.

Personal Information
Dr. Jannette M. Dufour is currently a Professor in the Department of Cell Biology and Biochemistry in the School of Medicine at Texas Tech University Health Sciences Center and Associate Director of the Obesity Research Institute. She received her PhD in Genetics and Cell Biology from Washington State University in 1999 and trained as a postdoctoral fellow with the Islet Transplantation Group in the Surgical Medical Research Institute, Department of Surgery at the University of Alberta, Edmonton, Canada from 1999-2005.
The focus of her research is to explore the therapeutic potential of immune privileged
Sertoli cells as a means to improve outcomes of transplantation. Specifically, her
lab is testing the feasibility of using immune privileged Sertoli cells for cell based gene therapy and examining the mechanism(s) of Sertoli cell immune protection in
order to improve survival of insulin-expressing cells as a treatment for diabetes.
Her research has been funded by several national and local agencies including the
NIH, American Diabetes Association and Texas ARP and has been selected for the cover
photo for Cell Transplantation (2008), Spermatogenesis (2012) and DNA and Cell Biology (2018) and highlighted in Biology of Reproduction (2014) and Nature Medicine (2018). She has been invited to give seminars at several universities as well as
at national and international meetings, including American Society of Andrology (ASA;
2007, 2016), Society for the Study of Reproduction; 2012, 2016), NIAID (2017) and
NIEHS (2017). She has received the TTUHSC Presidents Young Investigator Award (2011), the Outstanding
Women Leader (OWL) Award from the West Texas Association for Women in Science (2013),
the Harry M. Weitlauf Anatomy Teaching Award (2013), the Deans Basic Science Teaching Award (2017) and
the Presidents Team Teaching Award (2019 and 2020).
Research Interests
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Importance of immune disregulation in diabetes
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Use of immune privileged Sertoli cells to improve treatment of diabetes
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Examining the use of transplanted Sertoli cells to protect co-transplanted islets and for gene therapy
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Examining the mechanism for Sertoli cell immune privilege and immunoprotection of transplanted cells
Future Research Collaboration Interests
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Diabetes
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Immune Regulation
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Transplantation
Center of Excellence in Obesity and Cardiometabolic Research
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Email
obesity.ori@ttu.edu