Texas Tech University

Breanna N. Harris, Ph.D.

Assistant Professor
Department of Biological Sciences

Email: breanna.n.harris@ttu.edu 

Phone: 1(806)834-6307  

 

picture of Breanna N. Harris, Ph.D.

Personal Information

  • Ph.D., Evolution, Ecology, and Organismal Biology. University of California, Riverside (2007-2012)
  • B.S., Marine Biology. Ohio University (2001-2005) 

Courses Taught  

  • Biology 4301-D79: Human Reproduction and Sexual Behavior, online
  • Biology 4301-079: Peer Mentoring in Human Physiology
  • Zoology 2404: Anatomy and Physiology II
  • Biology 4301-079: Human Reproduction and Sexual Behavior
  • Biology 4301-079: Brain, Behavior and Hormones 

 

Research Interests

Broadly, I am interested in how stressors, or challenges, influence organismal function and life-history tradeoffs. Using animal and human subjects, I study how stress-response-related differences at various biological levels of analysis correspond to differences in health, behavior, reproduction, and fitness. More specifically, I focus on the behavioral, physiological, and fitness implications of plasticity in “stress-response” systems, mainly the hypothalamic-pituitary-adrenal/interrenal (HPA/I) axis. The HPA/I axis is evolutionarily conserved and its hormonal end products, the glucocorticoids, are critical for survival, and play an important role in many physiological and behavioral processes including reproduction, immune system regulation, energy metabolism, memory and cognition, and cardiovascular function. Many human diseases and psychopathologies (e.g., PTSD, anxiety disorders, depression, obesity, Alzheimer's Disease, eating disorders) present with HPA axis dysregulation for unknown reasons and by unknown mechanisms. These wide-ranging effects make the HPA axis a well-suited system for studying the physiological underpinnings of life history trade-offs and for investigating human health trajectories and disease etiology.  

Currently, my research program addresses two central themes: 1) how does variation in response to and recovery from stressors translate into functional consequences in organismal behavior, cognition, risk-taking, feeding, health, life history trade-offs, and/or fitness, and 2) how do sensory perception, genotype, diet, sex, life history stage, and interactions with the environment alter physiological and/or behavioral responses to stressors. Both questions are important for understanding animal life histories, ecological interactions, and evolutionary trade-offs, and both are relevant to human health and disease. 

My work is integrative and comparative, and I take an organismal approach to research (e.g., what are the functional, organism-level consequences of physiological responses). I have used multiple species, including crabs, lobsters, sharks, frogs, mice, and humans to answer questions relating to stress physiology, behavior, and trade-offs.  

My research program has drawn media attention and I, or members of my lab, have appeared on segments of Fox34, Science News for Students, Texas Tech Today, and KTTZ-TV. My research projects are collaborative and undergraduate students play an integral role in my lab. Students interested in working in my lab should email me to ask for an application. 

In addition to research, I am passionate about education and outreach. As part of our NSF grant, Dr. James Carr and I co-curated a museum exhibit at the Museum of Texas Tech (Why Frogs Don’t Get Fat: Predators, Fear, and Feeding in the Wild). I was inducted into the TTU Teaching Academy in 2019. Due to my role in the active learning community, I had the opportunity to create an educational guide/case study for the Hollywood film, To Dust; the case study is available online. 

Selected Publications

For complete list of publications, please see the Google Scholar Page. 

 Harris, B.N. (2020). Stress hypothesis overload: 131 hypotheses exploring the role of stress in tradeoffs, transitions, and healthGeneral and Comparative Endocrinology, 288, 113355. https://doi.org/10.1016/j.ygcen.2019.113355 

 Harris, B.N., Hohman, Z.P., Campbell, C.M., King, K.S., Tucker, C.A. (2019). Interactions among FAAH genotype, CRFR1 genotype, and cortisol are related to anxiety in an aging, rural Hispanic population: A Project FRONTIER study. Neurobiology of Stress, 100154 

Coleman, R.B., Aguirre, K., Spiegel, H., Pecos, C., Carr, J.A., Harris, B.N. (2019). The plus maze and scototaxis test are not valid behavioral assays for anxiety assessment in the South African clawed frog. Journal of Comparative Physiology A, 205, 567-582. 

Niedbala, E.M., Hohman, Z.P., Harris, B.N., Abide, A.C. (2018). Taking one for the team: Physiological trajectories of painful intergroup retaliation. Physiology & Behavior, 194, 277-284. 

Saltzman, W., Harris, B.N., De Jong, T.R., Perea-Rodriguez, J.P., Horrell, N., Zhao, M., Andrew, J. (2017). Paternal Care in Biparental Rodents: Intra- and Inter-Individual Variation. Integrative and Comparative Biology, 57, 589-602. 

Harris, B.N.Carr, J.A. (2016). The role of the hypothalamus-pituitary-adrenal/interrenal axis in mediating predator-avoidance trade-offs. General and Comparative Endocrinology, 230-231, 110-142. 

Duggan, P.E., Prater, C., Carr, J.A., Harris, B.N. (2016). Predator presence decreases food consumption in juvenile African clawed frogs (Xenopus laevis). Behavioral Ecology and Sociobiology, 70, 2005-2015. 

Harris, B.N., de Jong, T.R., Yang, V., Saltzman, W. (2013). Chronic variable stress in fathers alters paternal and social behavior but not pup development in the biparental California mouse (Peromyscus californicus). Hormones and Behavior, 64, 799-811.