Texas Tech University

Andrew Shin, Ph.D.

Assistant Professor, Director, Mouse Metabolic Phenotyping Facility
Nutritional Sciences
Andrew Shin, Ph.D.

Personal Information

Dr. Andrew C. Shin obtained his doctoral degree in Neuroscience at Michigan State University in 2008 and completed his postdoctoral fellowships at Pennington Biomedical Research Center and Icahn School of Medicine at Mount Sinai where he became an instructor. He joined the Department of Nutritional Sciences here at TTU in 2016 as a research assistant professor. In late 2019, he was promoted to an assistant professor. 
 
Dr. Shin is interested in understanding how brain controls metabolism and nutrient partitioning as well as the long-term regulation of body weight and appetite and the underlying mechanisms of Roux-en-Y gastric bypass (RYGB) surgery. Dr. Shin's current NIH-funded research project aims to understand the role of insulin action in the brain in regulating branched-chain amino acid (BCAA) metabolism and how this central control can contribute to glucose homeostasis by using molecular, pharmacological, transgenic, surgical, and integrative physiological approaches. 

CV

Research Interest

  • Role of insulin action in the brain for the control of branched-chain amino acid (BCAA) metabolism and its neural mechanisms  

  • Role of BCAAs in glucose homeostasis through the use of integrative physiological pancreatic clamp technique  

  • Mechanisms underpinning the metabolic benefits by Roux-en-Y gastric bypass (RYGB) surgery 

  • Mapping neuronal circuits that govern reward vs. homestostatic need-driven feeding using Designer-Receptors-Exclusively-Activated-by-Designer-Drugs (DREADD) and optogenetics techniques  

  • Metabolic signatures related to diabetes and Alzheimer’s disease 

Future Research Collaboration Interests

  • Strategies to improve glycemic control and metabolic health in obesity and diabetes 

  • Macro- and micronutrient metabolism following bariatric surgery 

  • Diabetes and Alzheimer’s disease