Publications

Book Chapter

2. N. Li, A.P. Rickel, and Z. Hong*. On-site Differentiation of Human Mesenchymal Stem Cells into Vascular Cells on Extracellular Matrix Scaffold under Mechanical Stimulations for Vascular Tissue Engineering. Methods in Molecular Biology, Springer Nature. 2022;2375:35-46.

1. H.J. Sanyour, A.P. Rickel, and Z. Hong*. The Interplay of Membrane Cholesterol and Substrate on Vascular Smooth Muscle Biomechanics. Current Topics in Membranes, Elsevier. 2020, 86: 279-299.
 

Peer Reviewed Journal (*Corresponding author)

49. Khatiwada N, Hong Z. Potential Benefits and Risks Associated with the Use of Statins. Pharmaceutics. 2024 Feb 1;16(2):214.

48. J. Liu, A.P. Rickel, S. Smith, Z. Hong*, C. Wang*. Non-cytotoxic” doses of metal-organic framework nanoparticles increase endothelial permeability by inducing actin reorganization. Journal of Colloid and Interface Science, 2022, 634(15): 323-335.

47. A.P. Rickel, H.J. Sanyour, C.N. Kinser, N. Khatiwada, H. Vogel. Z. Hong*. Exploring the difference in the mechanics of vascular smooth muscle cells from wild type and apolipoprotein-E knockout mice. American Journal of Physiology-Cell Physiology, 2022, 323 (5): C1393-C1401.

46. A.P. Rickel, X. Deng, Daniel Engebretson, and Z. Hong*. Electrospun Nanofiber Scaffold for Vascular Tissue Engineering. Materials Science and Engineering: C, 2021, 112373.

45. J.M. Miszuk, Z. Liang, J. Hu, H.J. Sanyour, Z. Hong, H. Fong, H. Sun. Elastic Mineralized 3D Electrospun PCL Nanofibrous Scaffold for Drug Release and Bone Tissue Engineering. ACS Applied Bio Materials, 2021, 4(4): 3639–3648.

44. D. Kota, L. Kang, A.P. Rickel, J. Liu, S. Smith, Z. Hong*, C. Wang*. Low doses of metal-organic framework nanoparticles alter the actin organization and contractility of vascular smooth muscle cells. Journal of Hazardous Materials, 2021, 414:125514.

43. A.P. Rickel, H.J. Sanyour, N.A. Leyda, and Z. Hong*. Substrate Stiffness and Extracellular Matrix Proteins Synergistically Regulate Vascular Smooth Muscle Cell Migration and Cytoskeleton Orientation. ACS Applied Bio Materials, 2020, 3(4): 2360−2369.

42. H.J. Sanyour, N. Li, A.P. Rickel, H.M. Torres, R.H. Anderson, M. R. Miles, J.D. Childs, K.R. Francis, J. Tao and Z. Hong*. Statin-mediated cholesterol depletion exerts coordinated effects on the alterations in rat vascular smooth muscle cell biomechanics and migration. The Journal of Physiology-London, 2020, 598(8): 1505-1522.  *Highlighted by a Journal Club.

41. X. Shi, S. Cui, X. Song, A.P. Rickel, H.J. Sanyour, J. Zheng, J. Hu, Z. Hong*, Y. Zhou, Yichun Liu. Gelatin-crosslinked pectin nanofiber mats allowing cell infiltration. Materials Science and Engineering: C, 2020, 112: 110941.

40. N. Li, F. Xue, H. Zhang, H.J. Sanyour, A.P. Rickel, A. Uttecht, B. Fanta, J. Hu, Z. Hong*.  Fabrication and Characterization of Pectin Hydrogel Nanofiber Scaffolds for Differentiation of Mesenchymal Stem Cells into Vascular Cells. ACS Biomaterials Science & Engineering, 2019, 5(12): 6511-6519.

39. N. Li, P.A. Rickel, H.J. Sanyour, and Z. Hong*. Vessel Graft Fabricated by the On-site Differentiation of Human Mesenchymal Stem Cells Toward Vascular Cells on Vascular Extracellular Matrix Scaffold under Mechanical Stimulations in Bioreactor. Journal of Materials Chemistry B, 2019; 7: 2703-2713.

38. H.J. Sanyour, N. Li, A. Rickel, J.D. Childs, C. Kinser, Z. Hong*, Membrane Cholesterol and Substrate Stiffness Coordinate to Induce the Remodeling of the Cytoskeleton and the Alteration in the Biomechanics of Vascular Smooth Muscle Cells. Cardiovascular Research, 2019; 115: 1369-1380.  *Highlighted by an editorial commentary.

37. M. Madeo, P. Colbert, D. Vermeer, C. Lucido, J. Cain, E. Vichaya, A. Grossberg, D. Muirhead, A. Rickel, Z. Hong, J. Zhao, J. Weimer, W. Spanos, J. Lee, R. Dantzer, P. Vermeer. Cancer Exosomes Induce Tumor Innervation. Nature Communications, 2018; 9: 4284.

36. L. Xie, Z. Sun, Z. Hong, N. Brown, O. Glinskii, K. Rittenhouse-Olson, G.A. Meininger, V. Glinsky. Temporal and Molecular Dynamics of Human Metastatic Breast Carcinoma Cell Adhesive Interactions with Human Bone Marrow Endothelium Analyzed by Single-cell Force Spectroscopy, PLoS ONE, 2018; 13(9): e0204418.

35. N. Li, H.J. Sanyour, T. Remund, P. Kelly, Z. Hong*. Vascular Extracellular Matrix and Fibroblasts-coculture Directed Differentiation of Human Mesenchymal Stem Cells Toward Smooth Muscle-like Cells for Vascular Tissue Engineering. Materials Science and Engineering: C, 2018; 93: 61-69.

34. T. Xu, Q. Yao, J.M. Miszuk, H.J. Sanyour, Z. Hong, H. Sun, H. Fong, Tailoring Weight Ratio of PCL/PLA in Electrospun Three-dimensional Nanofibrous Scaffolds and the Effect on Osteogenic Differentiation of Stem Cells, Colloids and Surfaces B: Biointerfaces, 2018, 171: 31-39.

33. H.J. Sanyour, J.D. Childs, G.A. Meininger, Z. Hong*, Spontaneous Oscillation in Cell Adhesion and Stiffness Measured Using Atomic Force Microscopy. Scientific Reports, 2018; 8(1): 2899.

32. J.M. Miszuk, T. Xu, Q. Yao, F. Fang, J.D. Childs, Z. Hong, J. Tao, H. Fong, H. Sun. Functionalization of PCL-3D Electrospun Nanofibrous Scaffolds for Improved BMP2-induced Bone Formation, Applied Materials Today, 2017; 10: 194-202.

31. K. Hong, G. Zhao, Z. Hong, Z. Sun, Y. Yang, P.S. Clifford, M.J Davis, G.A. Meininger, M.A. Hill, Mechanical Activation of Angiotensin II Type 1 Receptors Causes Actin Remodelling and Myogenic Responsiveness in Skeletal Muscle Arterioles. The Journal of Physiology-London, 2016; 594(23): 7027-7047.

30. Z. Hong, K.J. Reeves, Z. Sun, Z. Li, N.J. Brown, and G.A. Meininger. Vascular Smooth Muscle Cell Stiffness and Adhesion to Collagen I Modified by Vasoactive Agonists. 2015 PLoS ONE, 2015; 10(3): e0119533.

29. N.L. Sehgel, Z. Sun, Z. Hong, W.C. Hunter, M.A. Hill, D.E. Vatner, S.F. Vatner, G.A. Meininger. Augmented Vascular Smooth Muscle Cell Stiffness and Extracellular Matrix Adhesion When Hypertension is Superimposed on Aging. Hypertension, 2015; 65(2): 370-377.

28. M.C. Staiculescu, F.I. Ramirez-Perez, J.A. Castorena-Gonzalez, Z. Hong, Z. Sun, G.A. Meininger, L.A. Martinez-Lemus. Lysophosphatidic Acid Induces Integrin Activation in Vascular Smooth Muscle and Alters Arteriolar Myogenic Vasoconstriction. Frontiers in Physiology, 2014; 5(413): 1-12.

27. Z. Hong, Z. Sun, M. Li, Z. Li, F. Bunyak, I. Ersoy, J.P. Trzeciakowski, M.C. Staiculescu, M. Jin, L. Martinez-Lemus, M.A. Hill, K. Palaniappan, and G.A. Meininger. Vasoactive Agonists Exert Dynamic and Coordinated Effects on Vascular Smooth Muscle Cell Elasticity, Cytoskeletal Remodeling and Adhesion. The Journal of Physiology-London, 2014; 592(6): 1249-1266. *Featured as journal cover and highlighted by an editorial commentary.

26. N.L. Sehgel, Y. Zhu, Z. Sun, J.P. Trzeciakowski, Z. Hong, W.C. Hunter, D.E. Vatner, G.A. Meininger, and S.F. Vatner. Increased Vascular Smooth Muscle Cell Stiffness: A Novel Mechanism for Aortic Stiffness in Hypertension. American journal of physiology. Heart and circulatory physiology 2013; 305: H1281-7.

25. Z. Hong, I. Ersoy, M. Sun, F. Bunyak, P. Hampel, Z. Hong, Z. Sun, Z. Li, I. Levitan, G.A. Meininger, and K. Palaniappan. Influence of Membrane Cholesterol and Substrate Elasticity on Endothelial Cell Spreading Behavior. Journal of Biomedical Materials Research A 2013; 101A: 1994-2004.

24. Z. Hong, Z. Sun, Z. Li, W.T. Mesquitta, J.P. Trzeciakowski, and G.A. Meininger. Coordination of Fibronectin Adhesion with Contraction and Relaxation in Microvascular Smooth Muscle. Cardiovascular Research 2012; 96(1): 73-80.  *Highlighted by an editorial commentary.

23. Z. Hong, M.C. Staiculescu, P. Hampel, I. Levitan, G. Forgacs. How Cholesterol Regulates Endothelial Biomechanics. Frontiers in Physiology 2012; 3: 426. *Highlighted by an editorial commentary.

22. Y. Zhu, H. Qiu, J.P. Trzeciakowski, Z. Sun, Z. Li, Z. Hong, M.A. Hill, W.C. Hunter, D.E. Vatner, S. F. Vatner, G.A. Meininger. Temporal Analysis of Vascular Smooth Muscle Cell Elasticity and Adhesion Reveals Oscillation Waveforms That Differ with Aging. Aging Cell 2012;11(5): 741-750.

21. P. Zhang, H. Wu, H. Wu, Z. Lu, C. Deng, Z. Hong, X. Jing, and X. Chen. RGD-Conjugated Copolymer Incorporated into Composite of Poly(lactide-co-glycotide) and Poly(l-lactide)-Grafted Nanohydroxyapatite for Bone Tissue Engineering. Biomacromolecules 2011; 12(7): 2667-2680.

20. A.R. Boccaccini, M. Erol, W.J. Stark, D. Mohn, Z. Hong, and J.F. Mano. Polymer/Bioactive Glass Nanocomposites for Biomedical Applications. Composites Science and Technology 2010; 70(13):1764-1776.

19. Z. Hong, Luz Gisela, P. Hampel, M. Jin, A. Liu, X. Chen, and J.F. Mano. Monodispersed Bioactive Glass Nanosphere: Preparation and Its Effects on Biomechanical Property of Mammalian Cells. Journal of Biomedical Materials Research A 2010; 95(3): 747-54.

18. Z. Hong. Recent Developments in Bioactive Ceramic/Glass: Preparation and Application in Tissue Engineering and Drug Delivery. Recent Patents on Materials Science 2010; 3(3): 239-257.

17. Z. Hong, M.G. Esther, R.L. Reis, and J.F. Mano. Novel Rice-shaped Bioactive Ceramic Nanoparticles. Advanced Engineering Materials 2009; 11: B25-B29. *Featured as journal cover

16. Z. Hong, A. Liu, L. Chen, X. Chen, and X. Jing. Preparation of Bioactive Glass Ceramic Nanoparticles by Combination of sol-gel and Coprecipitation Method. Journal of Non-Crystalline Solids 2009; 355: 368-372.

15. P. Zhang, Z. Hong, T. Yu, X. Chen, and X. Jing. In vivo Mineralization and Osteogenesis of Nano-composite Scaffold of Poly(lactide-co-glycolide) and Hydroxyapatite Surface-grafted with Poly(L-lactide). Biomaterials 2009; 30: 58-70.

14. Z. Hong, R.L Reis, and J.F. Mano. Preparation and In vitro Characterization of Novel Bioactive Glass Ceramic Nanoparticles. Journal of Biomedical Materials Research A 2009; 88: 304-313.

13. D.S. Couto, Z. Hong, and J.F. Mano. Development of Bioactive and Biodegradable Chitosan-based Injectable Systems Containing Bioactive Glass Nanoparticles. Acta Biomaterialia 2009; 5: 115-123.

12. Z. Hong, R.L Reis, and J.F. Mano. Preparation and In vitro Characterization of Scaffolds of Poly(L-lactic acid) Containing Bioactive Glass Ceramic Nanoparticles. Acta Biomaterialia 2008; 4: 1297-1306.

11. A. Liu, Z. Hong, X. Zhuang, X. Chen, Y. Cui, Y. Liu, and X. Jing. Surface Modification of Bioactive Glass Nanoparticles and the Mechanical and Biological Properties of Poly(L-lactide) Composites, Acta Biomaterialia 2008; 4: 1005-1015.

10. Z. Hong, P. Zhang, A. Liu, Chen Li, X. Chen, and X. Jing. Composites of poly(lactide-co-glycolide) and the Surface Modified Carbonated Hydroxyapatite Nanoparticles. Journal of Biomedical Materials Research A 2007; 81: 515-522.

9. X. Xu, X. Chen, A. Liu, Z. Hong and X. Jing. Electrospun Poly(L-lactide)-grafted Hydroxyapatite/poly(L-lactide) Nanocomposite Fibers. European Polymer Journal 2007; 43: 3187-3196.

8. C. He, J. Sun, T. Zhao, Z. Hong, X. Zhuang, X. Chen, and X. Jing. Formation of a Unique Crystal Morphology for the Poly(ethylene glycol)-Poly(ε-caprolactone) Diblock Copolymer. Biomacromolecules 2006; 7(1): 252-258.

7. L. Chen, X. Qiu, Z. Xie, Z. Hong, J. Sun, X. Chen and X. Jing. Poly(l-lactide)/starch Blends Compatibilized with Poly(l-lactide)-g-starch Copolymer. Carbohydrate Polymers 2006; 65: 75-80.

6. Z. Hong, P. Zhang, C. He, X. Qiu, A. Liu, L. Chen, X. Chen, and X. Jing. Nano-composite of Poly(L-lactide) and Surface Grafted Hydroxyapatite: Mechanical Properties and Biocompatibility. Biomaterials 2005; 26: 6296-6304.

5. X. Qiu, Z. Hong, J Hu, L. Chen, X. Chen, and X. Jing. Hydroxyapatite Surface Modified by L-Lactic Acid and Its Subsequent Grafting Polymerization of L-Lactide. Biomacromolecules 2005; 6(3): 1193-1199.

4. L. Chen，X. Qiu, M. Deng, Z. Hong, R. Luo, X. Chen, and X. Jing. The Starch Grafted Poly(L-lactide) and the Physical Properties of its Blending Composites. Polymer 2005; 46: 5723-5729.

3. X. Qiu, L. Chen, J. Hu, J. Sun, Z. Hong, A. Liu, X. Chen, and X. Jing. Surface-modified Hydroxyapatite Linked by L-lactic Acid Oligomer in the Absence of Catalyst. Journal of Polymer Science Part A 2005; 43(21): 5177-5185.

2. J. Sun, Z. Hong, L. Yang, Z. Tang, X. Chen, and X. Jing. Study on Crystalline Morphology of Poly(L-lactide)-poly(ethylene glycol) Diblock Copolymer. Polymer 2004; 45: 5969-5977.

1. Z. Hong, X. Qiu, J. Sun, M. Deng, X. Chen, and X. Jing. Grafting Polymerization of L-Lactide on the Surface of Hydroxyapatite Nanocrystals. Polymer 2004; 45: 6699-6706.
 

TEACHING

ME5358: Biomaterials (TTU)

ME4330: Biomaterials (TTU)

 

NEWS

01/01/2023: Hashem Saker and Rakibul Islam joined lab. Welcome!

08/22/2022, In collaboration with Dr Congzhou Wang at South Dakota School of Mines & Technology, The paper “Non-cytotoxic” doses of metal-organic framework nanoparticles increase endothelial permeability by inducing actin reorganization” has been published on line in Journal of Colloid and Interface Science. Congratulations!

09/19/2022: The paper “Exploring the difference in the mechanics of vascular smooth muscle cells from wild-type and apolipoprotein-E knockout mice” has been published online in American Journal of Physiology-Cell Physiology. Congratulations!

08/22/2022: Moved to Mechanical Engineering Department, Texas Tech University.