Nikhil Dhurandhar, Ph.D.
Phone: (806) 834-6446
Room: HS 402D
President, The Obesity Society (2014-15)
Department of Nutritional Sciences
As a physician and nutritional biochemist, Dr. Dhurandhar has been involved with obesity
treatment and research for over 20 years and has treated over 10,000 patients for
obesity using lifestyle therapy as well as pharmacological approaches. He believes
that simple explanations for causes of obesity are inadequate and novel approaches
are required for its effective management. He coined the term “Infectobesity” to describe
obesity of infectious origin. Dr. Dhurandhar et al were the first to identify adipogenic
effects of an avian adenovirus (SMAM-1) and a human adenovirus (Ad36) that cause obesity
in animals including rodents and monkeys, and are associated with obesity in humans
and non-human primates. In a recent series of studies, Dr. Dhurandhar et al identified
a novel adenoviral protein that could be exploited for its anti-diabetic properties.
The long term objectives of his work include the development of a vaccine to prevent
Ad36-induced obesity, and the development of anti-diabetic drugs based on the template
provided by the viral protein. Dr. Dhurandhar has received research funding from
the NIH, American Diabetes Association, Federal Emergency Management Agency, and other
non-profit or commercial funding sources, has published over 100 scientific articles,
and book chapters, and served as a mentor or advisor for several students and postdoctoral
EducationB.Sc. (Chemistry), M.S. (Nutrition), LCEH (Human Medicine), PhD (Biochemistry)
Dhurandhar NV and Thomas D. The Link Between Dietary Sugar Intake and Cardiovascular Disease Mortality - An Unresolved Question. JAMA 2015, Mar 3;313(9):959-60.
McAllister EJ, Dhurandhar NV, Keith SW, Aronne LJ, Barger J, Baskin M, Benca RM. Biggio J, Boggiano MM, Eisenmann JC, Elobeid M, Fontaine KR, Gluckman P, Hanlon EC, Katzmarzyk P, Pietrobelli A, Redden DT, Ruden DM, Wang CWaterland RA, Wright SM, Allison DB. 10 Putative Contributors to the Obesity Epidemic. Critical Reviews in Food Science and Nutrition 2009 Nov;49(10):868-913.
Dhurandhar NV. A framework for identifying infections that contribute to human obesity. Lancet Infectious Diseases – 2011; 11(12): 963-69. PMID: 22115071
Dhurandhar NV. Obesity: An Infectious Disease? In “Weight Management: State of the Science and Opportunities for Military Programs”. Institute of Medicine of the National Academies. The National Academies Press 2003, 224-228.
Lin WY, Dubuisson O, Rubicz R, Liu N, Allison DB, Curran JE, Comuzzie AG, Blangero J, Leach CT, Göring H, and Dhurandhar NV. Long term changes in adiposity and glycemic control are associated with past adenovirus infection. Diabetes Care 2013, 36(3):701-7. PMCID: PMC3579356