Texas Tech University

Nutritional Sciences

Nutrigenomics, Inflammation and Obesity Research Lab (NIOR)

Nishan Sudheera Kalupahana, MBBS, Ph.D.

Research Interests

  • Ethnic differences in body mass index-associated chronic disease risk (especially in Asian Populations)
  • Obesity, immune function and adipose tissue inflammation
  • Adipose tissue renin-angiotensin system (RAS) in the pathogenesis of insulin resistance
  • Mechanisms by which fatty acids (mainly omega-3 PUFAs) modulate adipose tissue function
  • Lifestyle interventions targeting obesity-associated co-morbidities including non-alcoholic fatty liver disease (NAFLD)

Proposed Collaborations

  • We have expertise in immunology techniques including flow cytometry and in vivo metabolic studies in rodents and would be happy to collaborate in translational research on obesity.
  • Our research group in Sri Lanka are conducting mechanistic and clinical studies in answering questions related to obesity, metabolic syndrome, type-2 diabetes and NAFLD with the aid of adipose tissue samples and imaging techniques in patients. We are looking for collaborators to enhance these analyses.

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Nutritional Sciences