Texas Tech University

Nutritional Sciences

Nutrigenomics, Inflammation and Obesity Research Lab (NIOR)

Nishan Sudheera Kalupahana, MBBS, Ph.D.
Recent Publications (2013-2017)

Book Chapters

  • Kalupahana NS, Jayalath T, Wang S and Moustaid-Moussa N. Regulation and metabolic effects of white adipose tissue SCD expression. In: Stearoyl Coenzyme-A Desaturase Genes in Lipid Metabolism. Edited by James M. Ntambi: Springer; 2013: 49-60
  • Kalupahana NS, Wang S, Rahman S and Moustaid-Moussa N. Function and regulation of macrophage SCD in metabolic disorders. In: Stearoyl Coenzyme-A Desaturase Genes in Lipid Metabolism. Edited by James M. Ntambi: Springer; 2013:61-71

Publications in peer-reviewed journals

  • Shi LZ, Kalupahana NS, Turnis ME, Neale G, Hock H, Vignali DA, Chi H. Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells. Proc Natl Acad Sci USA. 2013; 110(34):E3198-205
  • Fletcher SJ, Kalupahana NS, Bejnood M, Kim JH, Saxton AM, Wasserman D, De Taeye B, Voy BH, Quignard-Boulange A and Moustaid-Moussa N. Transgenic mice overexpressing renin exhibit glucose intolerance and diet-genotype interactions. Frontiers in Endocrinology, 2013 Jan 7;3:166
  • Siriwardhana N, Kalupahana NS, Cekanova M, Lemieux M, Greer B, Moustaid-Moussa N. Modulation of adipose tissue inflammation by bioactive food compounds. Journal of Nutritional Biochemistry, 2013 Apr;24(4):613-23
  • Carroll WX, Kalupahana NS, Booker SL, Siriwardhana N, Lemieux M, Saxton AM, Moustaid-Moussa N. Angiotensinogen gene silencing reduces markers of lipid accumulation and inflammation in cultured adipocytes. Front Endocrinol (Lausanne). 2013;4:10.
  • Somasundaram NP, Wijeyaratne CN, De Silva S, Siribaddana S, Illangasekera U, Rajaratnam H, Katulanda P, Bulugahapitiya U, Siyambalapitiya S, Antonypillai C, Sumanatilleke M, Katulanda G, Jayawardena P, Kalupahana NS et al. Diabetes Mellitus: Glucose Control. Sri Lanka Journal of Diabetes Endocrinology and Metabolism 2013; 3(1): 45-57
  • Abdel-Hamid T, Ankel F, Battle-Fisher M, Gibson B, Gonzalez-Parra G, Jalali M, Kaipainen K, Kalupahana NS et al. Public and health professionals' misconceptions about the dynamics of body weight gain/loss. System Dynamics Review 2014; 30(1-2): 58–74
  • Somasundaram N, Rajaratnam H, Wijeyarathne C, Katulanda P, De Silva S, Wickramasinghe P, Bulugahapitiya U, Siribaddana S, Siyambalapitiya S, Antonypillai C, Sumanathilake M, Garusinghe C, Muthukuda D, Niranjala MWS, Attapattu N, Kalupahana NS et al. Clinical guidelines: The Endocrine Society of Sri Lanka: Management of Obesity. Sri Lanka Journal of Diabetes, Endocrinology and Metabolism 2014; 1: 55-70
  • LeMieux MJ, Kalupahana NS, Scoggin S and Moustaid-Moussa N. Eicosapentaenoic acid induces adipocyte hypotrophy and reduces adipocyte inflammation in an adiposity-independent manner. Journal of Nutrition 2015; 145(3):411-7
  • Kalupahana NS, Jayalath T, Ralapanawa U. Prevention of non-communicable diseases- the time to act is now. Sri Lanka Journal of Medicine 2015; 24(1):1-2
  • LeMieux MJ, Mynatt R, Kalupahana NS, Kim JH, Ramalingam L, and Moustaid-Moussa N. Inactivation of Adipose Angiotensinogen Reduces Adipose Tissue Macrophages and Increases Adipose Cell Metabolic Activity. Obesity (Silver Spring) 2016 ;24(2):359-67
  • Somasundaram NP, Kalupahana NS. Population-based dietary approaches for the prevention of noncommunicable diseases. WHO South-East Asia J Public Health 2016; 5(1): 22–26
  • Pahlavani M, Razafimanjato F, Ramalingam L, Kalupahana NS, Moussa H, Scoggin S, Moustaid-Moussa N. Eicosapentaenoic acid regulates brown adipose tissue metabolism in high-fat-fed mice and in clonal brown adipocytes. Journal of Nutritional Biochemistry. 2016;39:101-109
  • Ramalingam L, Menikdiwela K, LeMieux M, Dufour JM, Kaur G, Kalupahana NS, Moustaid-Moussa N. The renin angiotensin system, oxidative stress and mitochondrial function in obesity and insulin resistance. Biochim Biophys Acta. 2016: S0925-4439(16)30187-9
  • Shi LZ, Zeng H, Kalupahana NS, Neale G and Chi H. Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes. Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E67-E74.
  • Jayawardana NWIA, Jayalath WATA, Madhujith WMT, Ralapanawa U, Jayasekera RS, Alagiyawanna SASB, Bandara AMKR, Kalupahana NS. Aging and obesity are associated with undiagnosed hypertension in a cohort of males in the Central Province of Sri Lanka: a cross-sectional descriptive study. BMC Cardiovasc Disord. 2017 Jun 21;17(1):165.
  • Goonapienuwala BL, Agampodi SB, Kalupahana NS, Siribaddana S. Body image construct of Sri Lankan adolescents. Ceylon Med J. 2017 Mar 31;62(1):40-46.
  • Jayawardana NW, Jayalath WA, Madhujith WM, Ralapanawa U, Jayasekera RS, Alagiyawanna SA, Bandara AM, Kalupahana NS. Lifestyle factors associated with obesity in a cohort of males in the central province of Sri Lanka: a cross-sectional descriptive study. BMC Public Health. 2017 Jan 5;17(1):27.
  • Allen L, Ramalingam L, Menikdiwela K, Scoggin S, Shen CL, Tomison MD, Kaur G, Dufour JM, Chung E, Kalupahana NS, Moustaid-Moussa N. Effects of Delta-Tocotrienol on Obesity-Related Adipocyte Hypertrophy, Inflammation, and Hepatic Steatosis in High Fat Fed Mice. J Nutr Biochem. 2017 Oct;48:128-137.
  • Pahlavani M, Kalupahana NS, Ramalingam L, Moustaid-Moussa N. Regulation and Functions of the Renin-Angiotensin System in White and Brown Adipose Tissue. Compr Physiol. 2017 Sep 12;7(4):1137-1150.


Nutritional Sciences