Magnetic Particle Spectroscopy Point-of-Care Device for Disease Diagnosis

Dr. Kai Wu

Texas Tech University
Department of Electrical and Computer Engineering

 

Abstract

The past decade has seen the continuous advancement of disease diagnostic platforms in a wide variety of research areas such as magnetic, optical, mechanical, and electrochemical sensing systems. However, there is an increasing demand for more accessible routine diagnostics for patients with respect to high accuracy, ease of use, and low cost. Magnetic biosensors have received extensive attention as promising candidates for next-generation disease diagnostic platforms. This approach is based on magnetic labels, rather than classical fluorescent labels, combined with magnetic sensors to detect stray fields from magnetic nanoparticle (MNP) labels. Since biological tissues and fluids are nonmagnetic or diamagnetic, there is negligible background noise from the complex biological samples, thus, it greatly benefits the higher signal-to-noise ratio of magnetic biosensors. In this talk, Dr. Wu will introduce the magnetic particle spectroscopy (MPS)-based biosensor. The working principles, the transition from lab-based assays to POC devices, and applications in disease diagnosis will be presented.

 

Speaker Biography

Dr. Wu is an Assistant Professor from Texas Tech University. He received his PhD in Electrical Engineering from the University of Minnesota, in 2017. He completed postdoctoral training at the University of Minnesota from 2017 to 2020. The research in Prof. Wu's lab focuses on new magnetic biosensors for healthcare applications, machine learning assisted magnetic imaging, synthesis of magnetic nanomaterials. He has published over 50 peer-reviewed papers, 6 US patents and 2 book chapters. He is the recipient of 3 IEEE Best Poster Awards and 2 IEEE Travel Awards. He has served as a guest editor for 4 journals and is a reviewer for more than 40 journals.