Texas Tech University

Nutritional Sciences

Nutrigenomics, Inflammation and Obesity Research Lab (NIOR)

Naïma Moustaïd-Moussa, Ph.D., FTOS., Professor & Director, Obesity Research Cluster

Recent Publications (2013-2018)

  1. Fletcher SJ, Kalupahana NS, Bejnood M, Kim JH, Saxton A, Wasserman D, de Taeye B, Voy BH, Quignard-Boulange A., and Moustaid-Moussa N. Overexpression of renin in the liver impairs glucose tolerance and insulin secretion. Front. Endocrin. (Diabetes issue), 3(166):1-9; (Jan 7) 2013
  2. Siriwardhana, N., Kalupahana, NS., Cekanova, M., Greer, B., LeMieux, M., Moustaid-Moussa, N., Modulation of adipose tissue inflammation by bioactive food compounds . J Nutr Biochem. 24(4):613-23, 2013
  3. Xin, W., Kalupahana, N., Booker, S.Siriwardhana, N., Lemieux, M. and Moustaid-Moussa, N. Adipose angiotensinogen silencing decreases inflammation and adipogenesis. Front. Endocrin. (Diabetes issue); 4(10): 1-12, (Mar 11) 2013.
  4. Dodson, MV., Boudina, S., Albrecht, E., Bucci, L., Fernyhough-Culver, M., Wei, S., Bergen, W., Amaral, AJ., Moustaid-Moussa, N., Poulos, S., and Hausman GK. A long journey to effective obesity treatments: Is there light at the end of the tunnel? Exp. Biol. Med. In Press, 2013
  5. Goktas Z, Moustaid-Moussa N, Shen CL, Boylan M, Mo H, Wang S. Effects of bariatric surgery on adipokine-induced inflammation and insulin resistance. Front. Endocrinol. 4:69, 2013
  6. Wang, S., Moustaid-Moussa; Chen, L., Mo, H., Shastri, A., Sun, R., Bapat, P., and Shen, C.L. Novel insights of dietary polyphenols and obesity. Invited Review, J. Nutr. Biochem. 2013
  7. LeMieux, M., AL-Jawadi, A., Wang, Shu and Moustaid-Moussa, N. Metabolic Profiling in nutrition and metabolic disorders. Adv. in Nutrition. 4: 548–550, 2013
  8. LeMieux, L; Al-Jawadi, A., Wang, S. and Moustaid-Moussa, N. Metabolic Profiling in Nutrition and Metabolic. Adv. Nutr. 4: 548–550, 2013
  9. Wang, S., Su, R. Nie, S., Sun, M., Zhang, J., Wu, D., and Moustaid-Moussa, N. Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals. J. Nutr. Biochem. Invited Review, In Press, 2013
  10. Kalupahana, N.S., Jayalath, T., Wang, S. and Moustaid-Moussa, N. Regulation and metabolic effects of white adipose tissue SCD-1 expression; J.M. Ntambi (ed.) Stearoyl-CoA desaturase genes in lipid metabolism. Springer Science+Business Media, New York; DOI 10.1007/978-1-4614-7969-7_5; 2013
  11. Kalupahana, N.S., Wang, S., Rahman, S.M. and Moustaid-Moussa, N. Function and regulation of macrophage SCD1 in metabolic disorders. J.M. Ntambi (ed.), Stearoyl-CoA Desaturase Genes in Lipid Metabolism. Springer Science+Business Media New York; DOI 10.1007/978-1-4614-7969-7_6; 2013
  12. Wang, S., Miller, B., Matthan, N.R., Goktas, Z., Wu, D., Reed, D.B., Yin, X., Grammas, P., Moustaid-Moussa, N., Shen, C-L., Lichtenstein, A. Aortic Cholesterol Accumulation Correlates with Systemic Inflammation but not Hepatic and Gonadal Adipose Tissue Inflammation in LDL Receptor Null Mice. In press, Nutrition Research, 2013
  13. Wang, S., Moustaid-Moussa, N.; Chen, L., Mo, H., Shastri, A., Sun, R., Bapat, P., and Shen, C.L. Novel insights of dietary polyphenols and obesity. Invited Review, J. Nutr. Biochem. 25 (1):1-18; 2014
  14. Wang, S., Su, R. Nie, S., Sun, M., Zhang, J., Wu, D., and Moustaid-Moussa, N. Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals. J. Nutr. Biochem. 25 (4): 363-76; 2014
  15. LeMieux, L; Aljawadi, A., and Moustaid-Moussa, N. Nutrimetabolomics. Adv Nutr. 5(6):792-794; 2014
  16. Crowe KM, Allison D and Bioactive Food Components Conference Speakers (Naima Moustaid-Moussa one of 21 collaborators). Evaluating bioactive food components in obesity and cancer prevention. Crit Rev Food Sci Nutr. 55(5):732-734; 2015
  17. LeMieux, M., Kalupahana, N., Scoggin, S., and Moustaid-Moussa, N. EPA reduces adipocyte inflammation independent of adiposity. J. Nutr. 145(3):411-417, 2015.
  18. Sams, V., Blackledge, C., Wijayatunga, N., Barlow, P., Mancini, M., Mancini, G., and Moustaid-Moussa, N. Effect of Bariatric Surgery on Systemic and Adipose Tissue Inflammation. Surgical Endoscopy; 30(8):3499-504, 2016
  19. LeMieux M, Ramalingam L, Mynatt R, Kalupahana N, Kim J, Moustaid-Moussa N. Inactivation of Adipose Angiotensinogen Reduces Adipose Tissue Macrophages and Increases Adipose Cell Metabolic Activity. Obesity; 24(2):359-67; 2016
  20. Rahman, S.M., Baquero, K.C., Choudhury, M., Janssen, R.C., de la Houssaye, B.A., Sun, M., Miyazaki-Anzai, S., Wang, S., Moustaid-Moussa, N., Miyazaki, M., Friedman, J.E. C/EBPβ in bone marrow is essential for diet induced inflammation, cholesterol balance, and atherosclerosis. Atherosclerosis. 2016. Jul; 250:172-9, 2016
  21. Parkman, J.K., Mao, X., Dillon, X., Gudivada, A., Moustaid-Moussa, N., Saxton, A.M. and Kim, J.H. Genotype-dependent metabolic responses to semi-purified high-sucrose high-fat diets in the TALLYHO/Jng vs. C57BL/6 mouse during the development of obesity and type 2 diabetes. Exp. Clin. Endocrinol. Diabetes. 124(10):622-629, 2016
  22. Pahlavani, M., Razafimanjato, F., Kalupahana, N., Ramalingam, L., Moussa, H., Scoggin, S. and Moustaid-Moussa, N. Eicosapentaenoic Acid Regulates Brown Adipose Tissue Metabolism in High Fat Fed Mice and in Clonal Brown Adipocytes. J. Nutr. Biochem., 39:101-109, 2017
  23. Ramalingam, L., Menikdewella, K., LeMieux, L., Dufour, J., Kalupahana, N., and Moustaid-Moussa, N. The renin angiotensin system, oxidative stress and mitochondrial function in obesity and insulin resistance. Biochem. Biophys. Acta. Molecular basis for Disease. Biochim Biophys Acta. 1863(5):1106-1114, 2017
  24. S. Liyanage, R.S. Dassanayake, A. Bouyanfif, E. Rajakaruna, L. Ramalingam, N. Moustaid-Moussa, N. Abidi. Optimization of cryostat temperature conditions for trans-reflectance mode FTIR microspectroscopic imaging of biological tissues. MethodsX, 4; 118-127, 2017.
  25. Pahlavani, M., Kalupahana, N.S., Ramalingam, L., Moustaid-Moussa, N. Regulation and Functions of the Renin-Angiotensin System in White and Brown Adipose Tissue. Compr. Physiol. 7(4):1137-1150; 2017
  26. Li S, Ning H, Ye Y, Wei W, Guo R, Song Q, Liu L, Liu Y, Na L, Niu Y, Chu X, Feng R, Moustaid-Moussa N, Li Y, Sun C. Increasing extracellular Ca2+ sensitizes TNF-alpha-induced vascular cell adhesion molecule-1 (VCAM-1) via a TRPC1/ERK1/2/NFκB-dependent pathway in human vascular endothelial cells. Biochim Biophys Acta. (Mol. Cell Res.) 2017 Jun 3;1864(10):1566-1577.
  27. Pahlavani, M., Ramalho, T, Jayarathne, S., Koboziev, I., Ramalingam. L., Filgueiras, L.R., Moustaid-Moussa, N. Adipose tissue inflammation in insulin resistance: Review of mechanisms mediating anti-inflammatory effects of omega-3 polyunsaturated fatty acids. J. Inv. Med. 65(7):1021-1027; 2017
  28. Allen, L., Ramalingam, L., Menikdiwela, M., Scoggin., Shen, C.L., Tomison, M.D., Kaur, G., Dufour, J., Chung, E., Kalupahana, N.S., Moustaid-Moussa, N. Effects of δ-Tocotrienol on Obesity-Related Adipocyte Hypertrophy, Inflammation, and Non-Alcoholic Fatty Liver Disease in High Fat Fed Mice. J. Nutr. Biochem. 48:128-137, 2017
  29. Bouyanfif A, Liyanage S, Hewitt JE, Vanapalli SA, Moustaid-Moussa N, Hequet E, Abidi N. FTIR imaging detects diet and genotype-dependent chemical composition changes in wild type and mutant C. elegans strains. Analyst. 142(24):4727-4736; 2017
  30. Jayarathne, S., Koboziev, I., Park, O.H., Oldewage-Theron, W., Shen, C.L., Moustaid-Moussa, N. Anti-Inflammatory and Anti-Obesity Properties of Food Bioactive Components: Effects on Adipose Tissue. Prev. Nutr. Food. 22(4), 251-262.
  31. Aljawadi, A., Moussa, H., Ramalingam, L., Dharamawardhane, S., Gollahon, L., Gunaratne, P., Rahman R., and Moustaid-Moussa, N. Protective properties of n-3 fatty acids and implications in obesity-associated breast cancer. J. Nutr. Biochem. 53:1-8; 2017.
  32. D'Costa, B.., Moustaid-Moussa, N., Gollahon, L.S. The Role of Exosomes in Breast Cancer: What Have We Learned in Ten Years? (Chapter 1) In: Triple-Negative Breast Cancer: Biomarkers, Emerging Therapeutic Strategies and Clinical Challenges. Editors: Marion Montgomery. Nova Science Publishers. Series: Cancer Etiology, Diagnosis and Treatments. ISBN: 978-1-53612-372-2; 2017
  33. Wijayatunga N, Pahlavani M, Kottapalli R., Dawson J, Gunaratne P., Coarfa C., Rajapakshe K., Kalupahana N., Moustaid-Moussa N. Adipose Depot-Specific Differences in Transcriptome and MicroRNA Expression in High Fat Diet Induced Obese Mice. Oncotarget. 9:9246-9261, 2018 https://doi.org/10.18632/oncotarget.24226
  34. Wijetunge, S., Kalupahana, NS., Ratnayake, RMCJ., Kotakadeniya, HMSRB., Rosairo, S., Albracht-Schulte, K., Ramalingam, L., and Moustaid-Moussa, N. Serum resistin and visceral adipocyte hypertrophy are associated with dysglycemia in South Asian women. J. Clin. Endo. Metab. Pending Review
  35. Pahlavani M, Wijayatunga N., Kottapalli R., Dawson J, Gunaratne P., Coarfa C., Rajapakshe K., Kalupahana N., Moustaid-Moussa N. Transcriptome and miRNA profiling in brown adipose tissue of high fat fed mice supplemented with eicosapentaenoic acid. Biochem. Biophys. Acta Mol Cell Lipids. Pending Review


Nutritional Sciences