Neurobiology of Nutrition Laboratory

Overview

We are interested in how the brain is able to integrate nutrient-related signals from various tissues in the body to control body weight and appetite, as well as nutrient metabolism (glucose, amino acids, lipids) in the context of obesity and diabetes. Related to this, we also study how Roux-en-Y gastric bypass (RYGB), a type of bariatric surgery considered to be one of the most effective treatments for obesity/diabetes, successfully lowers body weight and improves metabolic outcomes. How RYGB surgery rewires both "homeostatic" and "hedonic/reward" systems to defend the new lower body weight is a very interesting topic. We are also interested in parsing out the relationship between diabetes and Alzheimer's disease (AD), and in identifying novel biomarkers and treatments for AD.