Neurobiology of Nutrition Laboratory

Home | Research | People | Publications | Gallery | News and Announcements

Research Interests

Dr. Shin's lab is interested in how the brain controls metabolism and nutrient partitioning as well as the long-term regulation of body weight and appetite. The main research project aims to understand the role of insulin action in the brain in regulating branched-chain amino acid (BCAA) metabolism and how this central control can contribute to glucose homeostasis by using molecular, pharmacological, transgenic, surgical, and integrative physiological approaches.

Other ongoing research projects:

• Association between Type 2 diabetes and Alzheimer's disease
• Effects of Roux-en-Y gastric bypass (RYGB) surgery on appetite, hedonics, and reward control and the underlying mechanisms
• Understanding how nicotine affects blood glucose

Current Funding

• NIH R01 AG071560-01A1

  • Serotonin-modulated mitochondrial dysfunction in dementia, depression and diabetes, Feb 2022 – Jan 2027

     

    (PI: Arubala Reddy; Co-I: Andrew C. Shin)
• NIH R21 AG069140-01
  • BCAAs as a novel biomarker and treatment for Alzheimer's disease, Sep 2020 – Aug 2022
• Scientific & Technological Research Council of Turkey
  • The effects of central and systemic irisin on glucose homeostasis in diet-induced obese mice, Nov 2020 – Oct 2022
• Wylie Briscoe Fund, College of Human Sciences, TTU

  • Serum metabolomics in women with Alzheimer's disease, Dec 2021 – Dec 2022

    (PI: Andrew C. Shin)